Education:

• M.Sc. (with high distinction), Chemistry, Moscow State University, 1981. Thesis: Chemical determinism in genetic code: correlation of chemical parameters of amino acids and their anticodon nucleotides
• Ph.D. Biochemistry, Moscow State University, 1988. Dissertation: ATP/ADP antiporter is involved in fatty acid-induced uncoupling of oxidative phosphorylation in skeletal muscle mitochondria

Current research topics:

• Subcellular localization of lipids in macrophages
• Macrophage production of novel oxylipins (derivatives of eicosapentaenoic, docosahexaenoic and adrenic acid)
• Regulation of oxilipin production, mitochondrial function and oxidative stress in stimulated macrophages on the protein expression level

Publications:

• L.S. Iaguzhinskii, A. Andreev. Genetic code. The correlation between codon structural elements and the chemical properties of amino acids. Nauchnye Dokl. Vyss. Shkoly Biol. Nauki [Biological Sciences], 1982, (7), 21-24.
• A. Andreev, L.S. Iaguzhinskii. Unambiguous correspondence and complementarity of the chemical properties of amino acids and anticodons of the genetic code. Nauchnye Dokl. Vyss. Shkoly Biol. Nauki. [Biological Sciences], 1986, (11),16-25.
• A.Yu. Andreev, E.N. Mokhova, V.P. Skulachev, N.I. Volkov. Carboxyatractylate and adenosinediphosphate reduce an uncoupling effect of palmitic acid on skeletal muscle mitochondria. Biologicheskie membrany [Biological membranes], 1987, 4, 474-478.
• A.Yu. Andreyev, T.O. Bondareva, V.I. Dedukhova, E.N. Mokhova, V.P. Skulachev, N.I. Volkov. Carboxyatractylate inhibits the uncoupling effect of free fatty acids. FEBS Lett., 1988, 226, 265-269.
• A. Andreev, L.S. Iaguzhinskii. The conformity of chemical parameters of amino acids and anticodons in the genetic code. Zhurnal evolyutsionnoi biokhimii i fiziologii [J. of evolutionary biochemistry and physiology], 1988, 24, 121-128.
• L.S. Iaguzhinskii, A. Andreev. Chemical determinism of the genetic code: correlation of steric parameters of amino acids and anticodons. Zhurnal evolyutsionnoi biokhimii i fiziologii [J. of evolutionary biochemistry and physiology], 1988, 24, 746-757.
• A.Yu. Andreyev, T.O. Bondareva, V.I. Dedukhova, E.N. Mokhova, V.P. Skulachev, L.M. Tzofina, T.V. Vygodina. The ATP/ADP antiporter is involved in the uncoupling effect of fatty acids. In: Anion Carriers of Mitochondrial Membranes (Azzy et al. eds.), Springer-Verlag, Heidelberg, 1988.
• A.Yu. Andreyev, T.O. Bondareva, V.I. Dedukhova, E.N. Mokhova, V.P. Skulachev, L.M. Tzofina, N.I. Volkov, T.V. Vygodina. The ATP/ADP antiporter is involved in the uncoupling effect of fatty acids. Eur.J.Biochem., 1989, 187, 585-592.
• A.Yu. Andreev, V.I. Dedukhova, E.N. Mokhova. Uncoupling of oxidative phosphorylation in liver and skeletal muscle mitochondria by fatty acid in incubation medium of different ion composition. Biologicheskie membrany [Biological membranes], 1990, 7, 480-485.
• A.Yu. Andreyev, V.P. Skulachev, I.M. Tikhonova. Palmitic acid interaction with the ATP/ADP antiporter reconstituted into proteoliposomes. Biochemistry (Moscow), 1994, 59, 3-9.
• I.M. Tikhonova, A.Yu. Andreyev, Yu.N. Antonenko, A.D. Kaulen, A.Yu. Komrakov, V.P. Skulachev. Ion permeability induced in artificial membranes after bovine heart ATP/ADP antiporter incorporation. Biologicheskie membrany [Biological membranes], 1994, 11, 620-630.
• I.M. Tikhonova, A.Yu. Andreyev, Yu.N. Antonenko, A.D. Kaulen, A.Yu. Komrakov, V.P. Skulachev. Ion permeability induced in artificial membranes by the ATP/ADP antiporter. FEBS Letters, 1994, 337, 231-234.
• A.Yu. Andreyev, L.M. Mikhaylova, A.A. Starkov. Resealing of permeability transition pore by cyclosporin A: role of Mg , adenine nucleotides and the conformation of ATP/ADP-antiporter. Biochemistry (Moscow), 1994, 59, 1589-1597.
• A.Yu. Andreyev, L.M. Mikhaylova, A.A. Starkov, Yu.E. Kushnareva. Ca2+ loading modulates potencies of cyclosporin A, Mg and ADP to recouple permeabilized rat liver mitochondria. Biochem. and Mol. Biol. Intern., 1994, 34, 367-373.
• Yu.E. Kushnareva, L.M. Mikhaylova, A.Yu. Andreyev. Low concentrations of cyclosporin A reseal permeability transition pore in inner mitochondrial membrane in absence of additional effectors. Biochemistry (Moscow), 1995, 60, 1510-1519.
• L.M. Mikhaylova, Yu.E. Kushnareva, A.Yu. Andreyev. Inhibitors of ADP/ATP antiporter induce two Ca-dependent uncoupling pathways in rat liver mitochondria. Biochemistry (Moscow), 1996, 61, 905-910.
• N.S. Gavrilova, L.A. Gavrilov, G.N. Evdokushkina, V.G. Semenova, A.L. Gavrilova, N.N. Evdokushkina, Y.E. Kushnareva, V.N. Kroutko, A.Yu. Andreyev. Evolution, mutations and human longevity: the study on European royal and noble families. Human Biology, 1998, 70, 799-804.
• A.Y. Andreyev, B.Fahy, G.Fiskum. Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition. FEBS Lett., 1998, 439, 373-376.
• A. Andreyev, G.Fiskum. Calcium induced release of mitochondrial cytochrme c by different mechanisms selective for brain versus liver. Cell Death and Differentiation, 1999, 6, 825-832.
• G. Fiskum, A.J. Kowaltowksi, A.Y. Andreyev, Y.E. Kushnareva, A.A. Starkov. Apoptosis-related activities measured with isolated mitochondria and digitonin-permeabilized cells. Methods Enzymol., 2000, 322, 222-34.
• K. Johnson, A. Jung, A. Murphy, A. Andreyev, J. Dykens, R. Terkeltaub. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis Rheum., 2000, 43,1560-70.
• Y. Kushnareva, A.N. Murphy, A. Andreyev. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. Biochem J., 2002, 368, 545-53.
• M. Jazayeri, A. Andreyev, Y. Will, M. Ward, C.M. Anderson, W. Clevenger. Inducible expression of a dominant negative DNA polymerase-gamma depletes mitochondrial DNA and produces a rho0 phenotype. J. Biol. Chem., 2003, 278, 9823-30.
• A.Yu. Andreyev, Y. E. Kushnareva, A.A. Starkov. Mitochondrial metabolism of reactive oxygen species. Biochemistry (Moscow), 2005, 70, 200-214. /REVIEW
• Y. E. Kushnareva, S.E. Wiley, M.W. Ward, A.Y. Andreyev, and A.N. Murphy. Excitotoxic injury to mitochondria isolated from cultured neurons. J. Biol. Chem., 2005, 280, 28894-902.
• J. Lee, C.-H. Kim, D.K. Simon, L. Aminova, A.Y. Andreyev, Y.E. Kushnareva, A.N. Murphy, B.E. Lonze, K.-S. Kim, D. Ginty, R.J. Ferrante, H. Ryu, and R. R. Ratan. Mitochondrial Cyclic AMP Response Element-Binding protein (CREB) mediates mitochondrial gene expression and neuronal survival. J. Biol. Chem., 2005, 280, 40398-40401.
• R. Yamaguchi, A.Y. Andreyev, A.N. Murphy, G.A. Perkins, M.H. Ellisman, and D.D. Newmeyer. Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity. Cell Death and Differentiation, 2007, 14, 616-624.
• R. Harkewicz, E. Fahy, A. Andreyev, and E.A. Dennis. Arachidonate-derived dihomoprostaglandin production observed in endotoxin-stimulated macrophage-like cells. J. Biol. Chem., 2007, 282, 2899-2910.