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Darren Dumlao, Ph.D.

Assistant Project Scientist

9500 Gilman Drive
La Jolla, CA 92093-0601
Phone: (858) 534 - 8903
Fax: (858) 534 - 7390
email: ddumlao@ucsd.edu
 
arrived: February 2008
Home Town:
 

Education:

  • B.S., Biochemistry, University of California, Los Angeles (2001)
  • Ph.D., Biochemistry and Molecular Biology, University of California, Los Angeles (2007)

Research topics:

  • Global eicosanoid profiles

Publications:

  • Katz JE, Dumlao DS, Clarke S, Hau J (2004) A new technique (COMSPARI) to facilitate the identification of minor compounds in complex mixtures by GC/MS and LC/MS: tools for the visualization of matched datasets, J Am Soc Mass Spectrom, 15, 580-4. PMID: 15047062
  • Katz JE, Dumlao DS, Wasserman JI, Lansdown MG, Jung ME, Faull KF, Clarke S (2004) 3-Isopropylmalate is the major endogenous substrate of the Saccharomyces cerevisiae trans-aconitate methyltransferase, Biochemistry, 43, 5976-86 (2004). PMID: 15147181
  • Dumlao DS, Hertz N, Clarke S (2008) Secreted 3-isopropylmalate methyl ester signals invasive growth during amino acid starvation in Saccharomyces cerevisiae, Biochemistry, 47, 698-709. PMID: 18092814
  • Quehenberger O, Armando A, Dumlao D, Stephens D, Dennis EA (2008) Lipidomics analysis of essential fatty acids in macrophages. Prostaglandins Leukot Essent Fatty Acids, 79, 123-9. PMID: 18996688
  • Buczynski MW, Dumlao DS, Dennis EA (2009) An integrated omics analysis of eicosanoid biology. J Lipid Res, 50, 1015-38. PMID: 19244215
  • Buczynski MW, Svensson C, Dumlao D, Fitzsimmons B, Shim JH, Scherbart T, Jacobsen FE, Hua XY, Yaksh TL, Dennis EA (2010) Inflammatory hyperalgesia induces essential bioactive lipid production in the spinal cord. J Neurochem, Epub ahead of print. PMID: 20492349
  • Harmon GS, Dumlao DS, Ng DT, Barrett KE, Dennis EA, Dong H, Glass CK (2010) Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in CFTR-deficient mice. Nature Medicine, 16, 313-8. PMID: 20154695
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