Postdoctoral Research Associate

Education:

• M.S. Biochemistry, University of California, Riverside, 2001
• Ph.D. Biochemistry, University of California, Riverside, 2006

Research topics:

• Activation mechanisms of GIV and GVI phospholipase A2

Publications:

• Hsu, Y.H., Wang, M.K., Pai, C.W. and Wang, Y.S. (2000), Sorption of 2,4-dichloro- phenoxy propionic acid by organo-clay complexes, Applied Clay Science V16, 3-4:147-159.
• Hsu YH, Burke JE, Stephens DL, Deems RA, Li S, Asmus KM, Woods VL Jr and Dennis EA. (2008), Calcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry. J Biol Chem. Apr 11;283(15):9820-7.
• Burke JE, Hsu YH, Deems RA, Li S, Woods VL Jr and Dennis EA. (2008) A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2. J Biol Chem. Nov 7;283(45):31227-36.
• Hsu YH, Johnson DA and Traugh JA, (2008) Analysis of Conformational Changes during Activation of Protein Kinase Pak2 by Amide Hydrogen/Deuterium Exchange. J Biol Chem. 283(52):36397-405.
• Hsu YH, Burke JE, Li S, Woods VL Jr and Dennis EA. Topology and Structure of Group VIA Ca2+-Independent Phospholipase A2 Interacting with Membranes Determined by Peptide Amide Hydrogen/Deuterium Exchange Mass Spectrometry (submitted).
• Barbayianni E, Stephens D, Grkovich A, Magrioti V, Hsu YH, Dolatzas P, Kalogiannidis D, Dennis EA and Kokotos G. 2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release
  based on dipeptides and pseudodipeptides (submitted).